PLA2G4A 抗体 (AA 31-80)
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北京 101111
Quick Overview for PLA2G4A 抗体 (AA 31-80) (ABIN6579286)
抗原
See all PLA2G4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-80
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原理
- cPLA2 Antibody
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特异性
- CPLA2 Polyclonal Antibody detects endogenous levels of cPLA2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human PLA2G4A. AA range:31-80
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
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别名
- PLA2G4A
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背景
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Synonyms: PLA2G4A, CPLA2, PLA2G4, Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA
Background: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],
Gene Name: PLA2G4A
Protein Name: Cytosolic phospholipase A2
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分子量
- 110 kDa
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基因ID
- 5321
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OMIM
- 600522
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UniProt
- P47712
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途径
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
抗原
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