CPE 抗体 (AA 427-476)
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Quick Overview for CPE 抗体 (AA 427-476) (ABIN6579266)
抗原
See all CPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 427-476
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原理
- CPE Antibody
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特异性
- CPE Polyclonal Antibody detects endogenous levels of CPE protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human CPE. AA range:427-476
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CPE (Carboxypeptidase E (CPE))
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别名
- CPE
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背景
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Synonyms: CPE, Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase
Background: carboxypeptidase E(CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],
Gene Name: CPE
Protein Name: Carboxypeptidase E
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分子量
- 53 kDa
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基因ID
- 1363
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OMIM
- 114855
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UniProt
- P16870
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途径
- Peptide Hormone Metabolism, Synaptic Membrane
抗原
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