PNPLA6 抗体 (AA 1031-1080)
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北京 101111
Quick Overview for PNPLA6 抗体 (AA 1031-1080) (ABIN6579261)
抗原
See all PNPLA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1031-1080
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原理
- NTE Antibody
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特异性
- NTE Polyclonal Antibody detects endogenous levels of NTE protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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别名
- PNPLA6
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背景
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Synonyms: PNPLA6, NTE, Neuropathy target esterase, Patatin-like phospholipase domain-containing protein 6
Background: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Gene Name: PNPLA6
Protein Name: Neuropathy target esterase
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分子量
- 149 kDa
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基因ID
- 10908
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OMIM
- 603197
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UniProt
- Q8IY17
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途径
- Ribonucleoside Biosynthetic Process
抗原
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