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RFX5 抗体 (AA 237-266)

This anti-RFX5 antibody is a 兔 多克隆 antibody detecting RFX5 in WB. Suitable for 人.
产品编号 ABIN657925
发货至: 中国

Quick Overview for RFX5 抗体 (AA 237-266) (ABIN657925)

抗原

See all RFX5 抗体
RFX5 (Regulatory Factor X 5 (RFX5))

适用

  • 29
  • 5
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  • 3
  • 3
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  • 2

宿主

  • 26
  • 3
  • 1

克隆类型

  • 28
  • 2
多克隆

标记

  • 26
  • 1
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  • 1
This RFX5 antibody is un-conjugated

应用范围

  • 28
  • 18
  • 6
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  • 1
Western Blotting (WB)

克隆位点

RB33870
  • 抗原表位

    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 237-266

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RFX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human RFX5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    RFX5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    RFX5 (Regulatory Factor X 5 (RFX5))

    别名

    RFX5

    背景

    A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq].

    分子量

    65323

    基因ID

    5993

    NCBI登录号

    NP_000440, NP_001020774

    UniProt

    P48382
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