Endothelin 1 抗体 (AA 131-180)
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Quick Overview for Endothelin 1 抗体 (AA 131-180) (ABIN6579220)
抗原
See all Endothelin 1 (EDN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-180
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原理
- ET-1 Antibody
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特异性
- ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
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亚型
- IgG
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Endothelin 1 (EDN1)
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别名
- EDN1
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背景
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Synonyms: EDN1, Endothelin-1, Preproendothelin-1, PPET1
Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: EDN1
Protein Name: Endothelin-1
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分子量
- 24 kDa
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基因ID
- 1906
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OMIM
- 131240
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UniProt
- P05305
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
抗原
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