JMJD2D 抗体 (AA 337-359)
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Quick Overview for JMJD2D 抗体 (AA 337-359) (ABIN6579170)
抗原
See all JMJD2D (KDM4D) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 337-359
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原理
- JMJD2D antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This JMJD2D antibody was raised against a peptide corresponding to amino acids 337-359 of human JMJD2D.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibody
KDM4D 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 1-523) antibodyKDM4D 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (N-Term) antibodyKDM4D 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 337-499) antibodyKDM4D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 434-483) antibodyKDM4D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 484-516), (C-Term) antibodyKDM4D 适用: 人 WB 宿主: 兔 Polyclonal RB10797 unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500 - 1:2,000 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
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别名
- JMJD2D
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背景
- JMJD2D (KDM4D) is a histone demethylase located in the nucleus that specifically demethylates Lysine 9 of Histone H3, thereby playing a central role in the histone code. JMJD2D (KDM4D) demethylates both di- and trimethylated histone H3 Lys 9, while it has no activity on monomethylated residues. The demethylation reaction of the Lys residue generates formaldehyde and succinate as a by product. In addition, JMJD2D forms a complex with the ligand-bound form of the Androgen Receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is associated with prostate cancer, suggesting that, via its ability to upregulate AR, JMJD2D (KDM4D) may be involved in carcinogenesis.
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分子量
- 58 kDa
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基因ID
- 55693
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NCBI登录号
- NP_060509
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途径
- Warburg Effect
抗原
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