TNK2 抗体 (AA 265-290)
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北京 101111
Quick Overview for TNK2 抗体 (AA 265-290) (ABIN657857)
抗原
See all TNK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 265-290
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预测反应
- B, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ACK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-290 amino acids from the Central region of human ACK1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- ACK1 Antibody (Center Y284) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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别名
- ACK1
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背景
- This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
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分子量
- 114569
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基因ID
- 10188
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NCBI登录号
- NP_001010938, NP_005772
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UniProt
- Q07912
抗原
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