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Nemo-Like Kinase 抗体 (C-Term)

This anti-Nemo-Like Kinase antibody is a 兔 多克隆 antibody detecting Nemo-Like Kinase in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN657850
发货至: 中国

Quick Overview for Nemo-Like Kinase 抗体 (C-Term) (ABIN657850)

抗原

See all Nemo-Like Kinase (NLK) 抗体
Nemo-Like Kinase (NLK)

适用

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人, 小鼠

宿主

  • 74
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克隆类型

  • 73
  • 5
多克隆

标记

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  • 1
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This Nemo-Like Kinase antibody is un-conjugated

应用范围

  • 70
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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB34651
  • 抗原表位

    • 15
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    • 2
    • 1
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    AA 408-436, C-Term

    预测反应

    B, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    Nemo-Like Kinase (NLK)

    别名

    Nlk

    背景

    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.

    分子量

    58313

    基因ID

    100044468, 18099

    NCBI登录号

    NP_032728

    UniProt

    O54949

    途径

    Ubiquitin Proteasome Pathway
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