KIR2DS1 抗体 (AA 151-180)
This 兔 多克隆 antibody specifically detects KIR2DS1 in ELISA 和 WB. It exhibits reactivity toward 人.
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产品编号 ABIN657823
发货至:
中国
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Quick Overview for KIR2DS1 抗体 (AA 151-180) (ABIN657823)
抗原
See all KIR2DS1 抗体
KIR2DS1
(Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This KIR2DS1 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
克隆位点
RB34046
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抗原表位
- AA 151-180
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KIR2DS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human KIR2DS1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- KIR2DS1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- KIR2DS1 (Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1))
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别名
- KIR2DS1
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背景
- Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
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分子量
- 33618
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基因ID
- 3806
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NCBI登录号
- NP_055327
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UniProt
- Q14954
抗原
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