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MBD3 抗体 (N-Term)

This anti-MBD3 antibody is a 兔 多克隆 antibody detecting MBD3 in WB. Suitable for 人.
产品编号 ABIN657677
发货至: 中国

Quick Overview for MBD3 抗体 (N-Term) (ABIN657677)

抗原

See all MBD3 抗体
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

适用

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  • 30
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  • 1
  • 1
  • 1

宿主

  • 56
  • 8
  • 2

克隆类型

  • 52
  • 14
多克隆

标记

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This MBD3 antibody is un-conjugated

应用范围

  • 42
  • 26
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  • 8
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  • 1
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Western Blotting (WB)

克隆位点

RB33769
  • 抗原表位

    • 8
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    • 4
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    • 1
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    AA 1-30, N-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MBD3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MBD3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    别名

    MBD3

    背景

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71 % and 94 % identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.

    分子量

    32844

    基因ID

    53615

    NCBI登录号

    NP_001268382, NP_001268383

    UniProt

    O95983

    途径

    Chromatin Binding
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