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PCDHGA3 抗体 (AA 284-311)

This anti-PCDHGA3 antibody is a 兔 多克隆 antibody detecting PCDHGA3 in FACS, WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN657534
发货至: 中国

Quick Overview for PCDHGA3 抗体 (AA 284-311) (ABIN657534)

抗原

See all PCDHGA3 (PCDHgA3) 抗体
PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))

适用

宿主

  • 8

克隆类型

  • 8
多克隆

标记

  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This PCDHGA3 antibody is un-conjugated

应用范围

  • 8
  • 8
  • 8
  • 8
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33029
  • 抗原表位

    • 6
    • 2
    • 2
    • 2
    AA 284-311

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PCDHGA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PCDHGA3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PCDHGA3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Zhang, Takata, Cui, Miyata-Takata, Sato, Noujima-Harada, Yoshino: "Protocadherin γ A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4622-4628, (2017) (PubMed).

  • 抗原

    PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))

    别名

    PCDHGA3

    背景

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

    分子量

    100971

    基因ID

    56112

    NCBI登录号

    NP_061739, NP_114400

    UniProt

    Q9Y5H0
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