Myomesin 1 抗体 (AA 904-933)
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Quick Overview for Myomesin 1 抗体 (AA 904-933) (ABIN657367)
抗原
See all Myomesin 1 (MYOM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 904-933
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This MYOM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the Central region of human MYOM1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- MYOM1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- Myomesin 1 (MYOM1)
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别名
- MYOM1
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背景
- The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 187627
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基因ID
- 8736
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NCBI登录号
- NP_003794, NP_062830
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UniProt
- P52179
抗原
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