ERO1L 抗体 (C-Term)
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Quick Overview for ERO1L 抗体 (C-Term) (ABIN657228)
抗原
See all ERO1L 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-379, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ERO1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-379 amino acids from the C-terminal region of human ERO1L.
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亚型
- Ig Fraction
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anti-ERO1-Like Protein alpha (ERO1L) (AA 90-178) antibody
ERO1L 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 90-178) antibodyERO1L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 24-260) antibodyERO1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 105-118) antibodyVerified ERO1L 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 321-420) antibodyERO1L 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 1-468) antibodyERO1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ERO1-Like Protein alpha (ERO1L) (AA 1-468) antibodyERO1L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- ERO1L (ERO1-Like Protein alpha (ERO1L))
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别名
- ERO1L
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背景
- Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress. Required for the folding of immunoglobulin proteins. Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin.
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分子量
- 54393
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NCBI登录号
- NP_055399
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UniProt
- Q96HE7
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途径
- Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
抗原
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