NSD1 抗体
Quick Overview for NSD1 抗体 (ABIN6572111)
抗原
See all NSD1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human NSD1
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亚型
- IgG
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anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) (AA 2-109) antibody
NSD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F1 unconjugated
anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) (AA 2401-2600) antibodyNSD1 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) (AA 2-109) antibodyNSD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) (AA 2-109) antibodyNSD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) antibodyNSD1 适用: 人 DB 宿主: 小鼠 Monoclonal 2658C1a unconjugated
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应用备注
- WB 1:500 - 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
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别名
- NSD1
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背景
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Synonyms: Nuclear Receptor Binding SET Domain Protein 1,Nuclear Receptor-Binding SET Domain-Containing Protein 1,Androgen Receptor-Associated Protein Of 267 KDa,Androgen Receptor Coactivator 267 KDa Protein,NR-Binding SET Domain-Containing Protein,Lysine N-Methyltransferase 3B,H3-K36-HMTase,H4-K20-HMTase,EC 2.1.1.43.
Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
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Observed_MW: 297kDa
Calculated_MW: 267kDa/284kDa/296kDa
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基因ID
- 64324
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UniProt
- Q96L73
抗原
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