RPE65 抗体
Quick Overview for RPE65 抗体 (ABIN6572041)
抗原
See all RPE65 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human RPE65
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亚型
- IgG
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anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibody
RPE65 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 348-484) antibodyRPE65 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 274-533) antibodyRPE65 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (Internal Region) antibodyVerified RPE65 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人, 小鼠, Cow, Pig, 小鸡, 非洲爪蟾 WB, IF, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 401-8B11-3D9 unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 7B10 unconjugated Recombinant Antibody
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
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别名
- RPE65
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背景
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Synonyms: All-trans-retinyl-palmitate hydrolase,LCA 2,LCA2,Leber congenital amaurosis ,mRPE 65,mRPE65,p63,rd 12,rd12,Retinal pigment epithelium specific 61 kDa protein,Retinal pigment epithelium specific 65 kDa protein,Retinal pigment epithelium specific protein ,Retinal pigment epithelium specific protein 65 kDa,Retinal pigment epithelium-specific 65 kDa protein,Retinitis pigmentosa 20 ,Retinoid isomerohydrolase,Retinol isomerase,RP 20,RP20,RPE 65,RPE65,RPE65,sRPE 65,sRPE65
Background: This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.
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分子量
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Observed_MW: 61kDa
Calculated_MW: 60kDa
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基因ID
- 6121
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UniProt
- Q16518
抗原
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