电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SPAG8 抗体

This anti-SPAG8 antibody is a 兔 多克隆 antibody detecting SPAG8 in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN6571917
发货至: 中国

Quick Overview for SPAG8 抗体 (ABIN6571917)

抗原

See all SPAG8 抗体
SPAG8 (Sperm Associated Antigen 8 (SPAG8))

适用

  • 51
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 47
  • 4

克隆类型

  • 49
  • 2
多克隆

标记

  • 22
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPAG8 antibody is un-conjugated

应用范围

  • 24
  • 19
  • 13
  • 13
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human SPAG8

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SPAG8 (Sperm Associated Antigen 8 (SPAG8))

    别名

    SPAG8

    背景

    Synonyms: BS 84,CILD28,HSD 1,HSD-1,HSD1,hSMP1,MGC26201,MH SPAG8,OTTHUMP00000021352,OTTMUSP00000032209,SMP-1,SMP1,SPAG3,SPAG8,SPAG8,Sperm associated antigen 8,Sperm associated antigen 8 like protein,Sperm membrane protein 1,Sperm membrane protein BS-84,Sperm-associated antigen 8,Testicular tissue protein Li 177

    Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

    分子量

    Observed_MW: 45kDa

    Calculated_MW: 44kDa/51kDa/53kDa

    基因ID

    26206

    UniProt

    Q99932
You are here:
Chat with us!