ITGA2 抗体
Quick Overview for ITGA2 抗体 (ABIN6571242)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
 - Affinity purification
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免疫原
 - Recombinant protein of human ITGA2
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亚型
 - IgG
 
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应用备注
 - WB 1:500 - 1:2000 IHC 1:100 - 1:200
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- ITGA2 (Integrin alpha 2 (ITGA2))
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别名
 - ITGA2
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背景
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Synonyms: BR,CD 49b,CD49 antigen like family member B,CD49 antigen-like family member B,CD49b,CD49b antigen,Collagen receptor,DX5,Glycoprotein Ia deficiency included,GP Ia,GP Ia deficiency,included,GPIa,HPA 5 included,HPA5 included,Human platelet alloantigen system 5,Integrin alpha 2,Integrin alpha II,Integrin alpha-2,Integrin,alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor),ITA2,ITGA2,Platelet alloantigen Br(a),included,Platelet antigen Br,Platelet glycoprotein GPIa,Platelet glycoprotein Ia,Platelet glycoprotein Ia/IIa,Platelet membrane glycoprotein Ia,Platelet receptor for collagen,deficiency of,included,Very late activation protein 2 receptor alpha 2 subunit,VLA 2 alpha chain,VLA 2,VLA 2 subunit alpha,VLA-2 subunit alpha,VLA2,VLA2 receptor alpha 2 subunit,VLAA2
Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
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分子量
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Observed_MW: 150kDa
Calculated_MW: 129kDa
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基因ID
 - 3673
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UniProt
 - P17301
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途径
 - CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
 
抗原
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