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WISP2 抗体

This anti-WISP2 antibody is a 兔 多克隆 antibody detecting WISP2 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6571151
发货至: 中国

Quick Overview for WISP2 抗体 (ABIN6571151)

抗原

See all WISP2 抗体
WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

适用

  • 45
  • 7
  • 5
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 42
  • 8

克隆类型

  • 43
  • 7
多克隆

标记

  • 32
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WISP2 antibody is un-conjugated

应用范围

  • 38
  • 18
  • 18
  • 12
  • 11
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human WISP2

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

    别名

    WISP2

    背景

    Synonyms: CCN family member 5,CCN5,Connective tissue growth factor like protein,Connective tissue growth factor related protein 58,Connective tissue growth factor-like protein,Connective tissue growth factor-related protein 58,CT58,CTGF L,CTGF-L,WISP 2,WISP-2,Wisp2,WISP2,Wnt 1 signaling pathway protein 2,WNT1 inducible signaling pathway protein 2,WNT1-inducible-signaling pathway protein 2

    Background: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

    分子量

    Observed_MW: 27kDa

    Calculated_MW: 22kDa/26kDa

    基因ID

    8839

    UniProt

    O76076

    途径

    WNT signaling, Growth Factor Binding
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