ZAK 抗体
Quick Overview for ZAK 抗体 (ABIN6571100)
抗原
See all ZAK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human ZAK (NP_598407.1).
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:50-1:200 IF 1:20-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
-
别名
- ZAK
-
背景
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
-
分子量
-
Observed_MW: 55kDa, 100kDa
Calculated_MW: 35kDa/51kDa/91kDa
-
基因ID
- 51776
-
UniProt
- Q9NYL2
抗原
-