ITM2B 抗体 (C-Term)
Quick Overview for ITM2B 抗体 (C-Term) (ABIN657087)
抗原
See all ITM2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 218-247, C-Term
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预测反应
- Pr
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ITM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human ITM2B.
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亚型
- Ig Fraction
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anti-Integral Membrane Protein 2B (ITM2B) (Internal Region) antibody
Verified ITM2B 适用: 人 ELISA, WB, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 81-148) antibodyITM2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 1-266) antibodyITM2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 1-266) antibodyITM2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 146-245) antibodyITM2B 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A10 unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- ITM2B (Integral Membrane Protein 2B (ITM2B))
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别名
- ITM2B
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背景
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
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分子量
- 30338
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NCBI登录号
- NP_068839
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UniProt
- Q9Y287
抗原
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