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GNAS 抗体 (C-Term)

Name: GNAS 抗体 (C-Term)
SKU: ABIN656989
Availability: OutOfStock

This 兔多克隆 anti-GNAS antibody (Clone RB33001) specifically detects GNAS in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 samples.

Western blot analysis of GNAS (arrow) using rabbit polyclonal GNAS Antibody (C-term) (ABIN656989 and ABIN2850497). (GNAS 抗体 (C-Term))

GNAS Antibody (C-term) (ABIN656989 and ABIN2850497) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (GNAS 抗体 (C-Term))

IHC (p)

GNAS Antibody (C-term) (ABIN656989 and ABIN2850497) western blot analysis in 293,NCI- cell line lysates (35 μg/lane). (GNAS 抗体 (C-Term))

Confocal immunofluorescent analysis of GNAS Antibody (C-term) (ABIN656989 and ABIN2850497) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (GNAS 抗体 (C-Term))

GNAS Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). (GNAS 抗体 (C-Term))

FACS

5 images

产品编号 ABIN656989

发货至: 中国

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Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GNAS 抗体 (C-Term) (ABIN656989)

抗原

See all GNAS 抗体

GNAS (GNAS Complex Locus (GNAS))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GNAS antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33001

Discover our top product GNAS Primary Antibody

抗原表位
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AA 287-315, C-Term

预测反应

M, Rat, B, Ha, Pig

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human GNAS.

亚型

IgG
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) antibody
KO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 310-404) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (Internal Region) antibody
Verified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 286-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

GNAS Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
抗原

GNAS (GNAS Complex Locus (GNAS))

别名

GNAS

背景

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.

分子量

44250

基因ID

2778

UniProt

Q5FWY2

途径

Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis