BCL6 抗体 (C-Term)
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Quick Overview for BCL6 抗体 (C-Term) (ABIN656985)
抗原
See all BCL6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 676-704, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BCL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 676-704 amino acids from the C-terminal region of human BCL6.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- BCL6 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- BCL6
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背景
- The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
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分子量
- 78846
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基因ID
- 604
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NCBI登录号
- NP_001124317, NP_001128210, NP_001697
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UniProt
- P41182
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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