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DUSP4 抗体

This anti-DUSP4 antibody is a 兔 多克隆 antibody detecting DUSP4 in WB. Suitable for 人 和 猴.
产品编号 ABIN6569333
发货至: 中国

Quick Overview for DUSP4 抗体 (ABIN6569333)

抗原

See all DUSP4 抗体
DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

适用

  • 58
  • 40
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 猴

宿主

  • 55
  • 4

克隆类型

  • 55
  • 4
多克隆

标记

  • 26
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP4 antibody is un-conjugated

应用范围

  • 45
  • 25
  • 22
  • 14
  • 13
  • 13
  • 9
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human DUSP4

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

    别名

    MKP-2

    背景

    Synonyms: Dual specificity phosphatase 4,Dual specificity protein phosphatase 4,Dual specificity protein phosphatase hVH2,DUS4,DUSP 4,Dusp4,HVH 2,HVH2,MAP kinase phosphatase 2,Mitogen activated protein kinase phosphatase 2,Mitogen-activated protein kinase phosphatase 2,MKP 2,MKP-2,MKP2,Serine/threonine specific protein phosphatase,TYP,Typ1,VH 2,VH1 homologous phosphatase 2,VH2

    Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

    分子量

    Observed_MW: 43kDa

    Calculated_MW: 32kDa/42kDa

    基因ID

    1846

    UniProt

    Q13115

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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