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CBX3 抗体

This anti-CBX3 antibody is a 兔 多克隆 antibody detecting CBX3 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6569197
发货至: 中国

Quick Overview for CBX3 抗体 (ABIN6569197)

抗原

See all CBX3 抗体
CBX3 (Chromobox Homolog 3 (CBX3))

适用

  • 107
  • 66
  • 49
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  • 7
  • 7
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  • 5
  • 5
  • 5
  • 4
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  • 1
人, 小鼠, 大鼠

宿主

  • 82
  • 26
  • 2

克隆类型

  • 75
  • 35
多克隆

标记

  • 57
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This CBX3 antibody is un-conjugated

应用范围

  • 57
  • 32
  • 30
  • 28
  • 27
  • 21
  • 18
  • 16
  • 10
  • 8
  • 5
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

质量等级

KO Validated
  • 特异性

    This antibody ist KO validated.

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human CBX3 (NP_009207.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CBX3 (Chromobox Homolog 3 (CBX3))

    别名

    CBX3

    背景

    At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

    分子量

    Observed_MW: 23kDa

    Calculated_MW: 20kDa

    基因ID

    11335

    UniProt

    Q13185
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