CBX3 抗体
Quick Overview for CBX3 抗体 (ABIN6569197)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- This antibody ist KO validated.
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human CBX3 (NP_009207.2).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3
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背景
- At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
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分子量
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Observed_MW: 23kDa
Calculated_MW: 20kDa
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基因ID
- 11335
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UniProt
- Q13185
抗原
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