CHD3 抗体
Quick Overview for CHD3 抗体 (ABIN6569189)
抗原
See all CHD3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purification
-
免疫原
- A synthetic peptide of human CHD3 (NP_001005273.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:200-1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
-
别名
- CHD3
-
背景
- This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
-
分子量
-
Observed_MW: 250kDa
Calculated_MW: 222kDa/226kDa/233kDa
-
基因ID
- 1107
-
UniProt
- Q12873
抗原
-