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- 抗原 See all CHRNA7 抗体
- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRNA7 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human CHRNA7 (NP_001177384.1).
- 亚型
- IgG
- Top Product
- Discover our top product CHRNA7 Primary Antibody
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anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 52-259) antibody
CHRNA7 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10G1 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 441-502) antibodyCHRNA7 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 52-259) antibodyCHRNA7 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10F1 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 23-230) antibodyCHRNA7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) antibodyCHRNA7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 23-230) antibodyCHRNA7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (N-Term) antibodyCHRNA7 适用: 人, 大鼠, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 31-42), (Extracellular), (N-Term) antibodyCHRNA7 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) antibodyCHRNA7 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (Internal Region) antibodyVerified CHRNA7 适用: 人, 大鼠 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
- 别名
- CHRNA7 (CHRNA7 产品)
- 别名
- CHRNA7-2 antibody, NACHRA7 antibody, dZ70B1.1 antibody, Acra7 antibody, alpha7 antibody, BTX antibody, NARAD antibody, nAChRa7 antibody, CHRNA7 antibody, cholinergic receptor nicotinic alpha 7 subunit antibody, neuronal acetylcholine receptor subunit alpha-7 antibody, cholinergic receptor, nicotinic, alpha 7 (neuronal) antibody, cholinergic receptor, nicotinic, alpha polypeptide 7 antibody, cholinergic receptor, nicotinic, alpha 7 antibody, CHRNA7 antibody, LOC100374356 antibody, chrna7 antibody, Chrna7 antibody, LOC100060521 antibody
- 背景
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 53kDa
Calculated_MW: 11kDa/56kDa/59kDa
- 基因ID
- 1139
- UniProt
- P36544
- 途径
- Synaptic Membrane
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