LRWD1 抗体
Quick Overview for LRWD1 抗体 (ABIN6568759)
抗原
See all LRWD1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human Lrwd1
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亚型
- IgG
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anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 1-30), (N-Term) antibody
LRWD1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29538 unconjugated
anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 4-33), (N-Term) antibodyLRWD1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:200 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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别名
- Lrwd1
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背景
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Synonyms: 1200011O22Rik,AU042569,AW548074,DKFZp434K1815,Leucine rich repeats and WD repeat domain containing 1,Leucine-rich repeat and WD repeat-containing protein 1,LRWD1,LRWD1,ORC-associated protein,ORCA,Origin recognition complex-associated protein
Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 65kDa
Calculated_MW: 70kDa
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基因ID
- 222229
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UniProt
- Q9UFC0
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途径
- Chromatin Binding
抗原
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