Myoferlin 抗体
Quick Overview for Myoferlin 抗体 (ABIN6568697)
抗原
See all Myoferlin (MYOF) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human MYOF (NP_038479.1).
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亚型
- IgG
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应用备注
- WB 1:200-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Myoferlin (MYOF)
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别名
- MYOF
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背景
- MYOF,FER1L3,myoferlin,Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
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分子量
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Observed_MW: 250kDa
Calculated_MW: 17kDa/46kDa/49kDa/179kDa/229kDa/233kDa/234kDa
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基因ID
- 26509
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UniProt
- Q9NZM1
抗原
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