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GRIA4 抗体 (AA 296-325)

Cited in 1 publication. This 兔 多克隆 anti-GRIA4 antibody (Clone RB30232) specifically detects GRIA4 in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN656865
发货至: 中国
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Quick Overview for GRIA4 抗体 (AA 296-325) (ABIN656865)

抗原

See all GRIA4 抗体
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

适用

  • 70
  • 56
  • 34
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 72
  • 2

克隆类型

  • 63
  • 11
多克隆

标记

  • 34
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRIA4 antibody is un-conjugated

应用范围

  • 61
  • 27
  • 23
  • 13
  • 13
  • 11
  • 9
  • 4
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB30232
  • 抗原表位

    • 15
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-325

    预测反应

    Pr, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    GRIA4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Muntané, Horvath, Hof, Ely, Hopkins, Raghanti, Lewandowski, Wray, Sherwood: "Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 6, pp. 1596-607, (2015) (PubMed).

  • 抗原

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    别名

    GRIA4

    背景

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].

    分子量

    100871

    基因ID

    2893

    NCBI登录号

    NP_000820, NP_001070711, NP_001070712, NP_001106283

    UniProt

    P48058

    途径

    PI3K-Akt Signaling
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