GRIA4 抗体 (AA 296-325)
Quick Overview for GRIA4 抗体 (AA 296-325) (ABIN656865)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 296-325
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预测反应
- Pr, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- GRIA4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 6, pp. 1596-607, (2015) (PubMed).
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Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 6, pp. 1596-607, (2015) (PubMed).
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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别名
- GRIA4
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背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].
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分子量
- 100871
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基因ID
- 2893
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NCBI登录号
- NP_000820, NP_001070711, NP_001070712, NP_001106283
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UniProt
- P48058
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途径
- PI3K-Akt Signaling
抗原
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