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RNASEH2A 抗体

This anti-RNASEH2A antibody is a 兔 多克隆 antibody detecting RNASEH2A in WB 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN6568584
发货至: 中国
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Quick Overview for RNASEH2A 抗体 (ABIN6568584)

抗原

See all RNASEH2A 抗体
RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

适用

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人, 大鼠

宿主

  • 23
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克隆类型

  • 26
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多克隆

标记

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This RNASEH2A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human RNASEH2A (NP_006388.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

    别名

    RNASEH2A

    背景

    The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

    分子量

    Observed_MW: 33kDa

    Calculated_MW: 33kDa

    基因ID

    10535

    UniProt

    O75792
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