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C9ORF72 抗体 (C-Term)

Cited in 3+ publications. This 兔 多克隆 anti-C9ORF72 antibody (Clone RB27382) specifically detects C9ORF72 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN656852
发货至: 中国
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Quick Overview for C9ORF72 抗体 (C-Term) (ABIN656852)

抗原

See all C9ORF72 抗体
C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

适用

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宿主

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克隆类型

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多克隆

标记

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This C9ORF72 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB27382
  • 抗原表位

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    AA 396-424, C-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This C9orf72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-424 amino acids from the C-terminal region of human C9orf72.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    C9orf72 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Davidson, Robinson, Rollinson, Pickering-Brown, Xiao, Robertson, Mann: "Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies." in: Amyotrophic lateral sclerosis & frontotemporal degeneration, Vol. 19, Issue 1-2, pp. 102-111, (2018) (PubMed).

    Sullivan, Zhou, Robins, Paushter, Kim, Smolka, Hu: "The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 51, (2017) (PubMed).

    Burberry, Suzuki, Wang, Moccia, Mordes, Stewart, Suzuki-Uematsu, Ghosh, Singh, Merkle, Koszka, Li, Zon, Rossi, Trowbridge, Notarangelo, Eggan: "Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease." in: Science translational medicine, Vol. 8, Issue 347, pp. 347ra93, (2017) (PubMed).

  • 抗原

    C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

    别名

    C9orf72

    分子量

    54328

    基因ID

    203228

    NCBI登录号

    NP_001242983, NP_060795, NP_659442

    UniProt

    Q96LT7
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