DAD1 抗体
Quick Overview for DAD1 抗体 (ABIN6568449)
抗原
See all DAD1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human DAD1
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亚型
- IgG
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anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibody
DAD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibodyDAD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B4-C8 unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-100) antibodyDAD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) antibodyDAD1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DAD1 (Defender Against Cell Death 1 (DAD1))
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别名
- DAD1
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背景
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Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2
Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
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分子量
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Observed_MW: 22kDa
Calculated_MW: 12kDa
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基因ID
- 1603
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UniProt
- P61803
抗原
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