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Coagulation Factor X 抗体

F10 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6568380
发货至: 中国
  • 抗原 See all Coagulation Factor X (F10) 抗体
    Coagulation Factor X (F10)
    适用
    • 63
    • 19
    • 16
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 49
    • 12
    • 10
    • 4
    • 2
    克隆类型
    • 62
    • 14
    多克隆
    标记
    • 47
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Coagulation Factor X antibody is un-conjugated
    应用范围
    • 41
    • 30
    • 16
    • 11
    • 11
    • 10
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human F10 (NP_000495.1).
    亚型
    IgG
    Top Product
    Discover our top product F10 Primary Antibody
  • 应用备注
    IF 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Coagulation Factor X (F10)
    别名
    F10 (F10 产品)
    别名
    FX antibody, FXA antibody, Cf10 antibody, fX antibody, fi12c10 antibody, wu:fi12c10 antibody, F10 antibody, f10 antibody, coagulation factor X antibody, Coagulation factor X antibody, coagulation factor 10 L homeolog antibody, F10 antibody, f10 antibody, CpipJ_CPIJ012712 antibody, CpipJ_CPIJ014863 antibody, CpipJ_CPIJ016937 antibody, CpipJ_CPIJ017791 antibody, fa10 antibody, f10.L antibody
    背景
    This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
    分子量

    Observed_MW: 75kDa

    Calculated_MW: 54kDa

    基因ID
    2159
    UniProt
    P00742
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