电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Coagulation Factor X 抗体

This anti-Coagulation Factor X antibody is a 兔 多克隆 antibody detecting Coagulation Factor X in IF. Suitable for 人 和 小鼠.
产品编号 ABIN6568380
发货至: 中国

Quick Overview for Coagulation Factor X 抗体 (ABIN6568380)

抗原

See all Coagulation Factor X (F10) 抗体
Coagulation Factor X (F10)

适用

  • 72
  • 22
  • 19
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 59
  • 12
  • 10
  • 7
  • 1

克隆类型

  • 72
  • 16
多克隆

标记

  • 56
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Coagulation Factor X antibody is un-conjugated

应用范围

  • 51
  • 36
  • 28
  • 15
  • 13
  • 10
  • 9
  • 9
  • 7
  • 7
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human F10 (NP_000495.1).

    亚型

    IgG
  • 应用备注

    IF 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Coagulation Factor X (F10)

    别名

    F10

    背景

    This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

    分子量

    Observed_MW: 75kDa

    Calculated_MW: 54kDa

    基因ID

    2159

    UniProt

    P00742
You are here:
Chat with us!