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COCH 抗体 (AA 399-428)

This anti-COCH antibody is a 兔 多克隆 antibody detecting COCH in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN656833
发货至: 中国

Quick Overview for COCH 抗体 (AA 399-428) (ABIN656833)

抗原

See all COCH 抗体
COCH (Cochlin (COCH))

适用

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宿主

  • 37
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克隆类型

  • 39
多克隆

标记

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This COCH antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB21184
  • 抗原表位

    • 8
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    AA 399-428

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human COCH.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    COCH Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    COCH (Cochlin (COCH))

    别名

    COCH

    背景

    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].

    分子量

    59483

    基因ID

    1690

    NCBI登录号

    NP_001128530, NP_004077

    UniProt

    O43405

    途径

    Sensory Perception of Sound
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