PLOD1 抗体
Quick Overview for PLOD1 抗体 (ABIN6568253)
抗原
See all PLOD1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human PLOD1
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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别名
- PLOD1
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背景
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Synonyms: 2-oxoglutarate 5-dioxygenase 1,EDS6,LH,LH1,LLH,Lysine hydroxylase,Lysyl hydroxylase 1,PLOD,Plod1,PLOD1,Procollagen lysine 1 2 oxoglutarate 5 dioxygenase 1,Procollagen lysine 2 oxoglutarate 5 dioxygenase 1,Procollagen-lysine
Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 83kDa/88kDa
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基因ID
- 5351
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UniProt
- Q02809
抗原
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