ARIP4 抗体
Quick Overview for ARIP4 抗体 (ABIN6568064)
抗原
See all ARIP4 (RAD54L2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human RAD54L2 (NP_055921.2).
-
亚型
- IgG
-
-
-
-
应用备注
- IF 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ARIP4 (RAD54L2) (RAD54-Like 2 (RAD54L2))
-
别名
- RAD54L2
-
背景
- Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.
-
分子量
-
Calculated_MW: 162kDa
-
基因ID
- 23132
-
UniProt
- Q9Y4B4
抗原
-