TBL1XR1 抗体
Quick Overview for TBL1XR1 抗体 (ABIN6567965)
抗原
See all TBL1XR1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human TBL1XR1
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000 IF 1:50 - 1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
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别名
- TBL1XR1
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背景
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Synonyms: C21,DC42,F box like/WD repeat containing protein TBL1XR1,F-box-like/WD repeat-containing protein TBL1XR1,FLJ12894,IRA1,Nuclear receptor corepressor/HDAC3 complex subunit,Nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1 related protein 1,TBL1-related protein 1,TBL1R,TBL1XR1,Transducin (beta) like 1 X linked receptor 1,Transducin beta like 1X related protein 1,Transducin beta-like 1X-related protein 1
Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
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分子量
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Observed_MW: 55-70kDa
Calculated_MW: 55kDa
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基因ID
- 79718
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UniProt
- Q9BZK7
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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