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APOB 抗体

This anti-APOB antibody is a 兔 多克隆 antibody detecting APOB in IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6567867
发货至: 中国

Quick Overview for APOB 抗体 (ABIN6567867)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 128
  • 35
  • 34
  • 10
  • 3
人, 小鼠, 大鼠

宿主

  • 91
  • 68
  • 14
  • 2
  • 2

克隆类型

  • 98
  • 77
多克隆

标记

  • 93
  • 27
  • 21
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APOB antibody is un-conjugated

应用范围

  • 113
  • 81
  • 64
  • 45
  • 44
  • 18
  • 17
  • 14
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human APOB (NP_000375.2).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    APOB

    背景

    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    分子量

    Observed_MW: 110kDa

    Calculated_MW: 515kDa

    基因ID

    338

    UniProt

    P04114

    途径

    Lipid Metabolism
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