MITF 抗体
Quick Overview for MITF 抗体 (ABIN5965832)
抗原
See all MITF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human MITF (NP_937801.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MITF (Microphthalmia-Associated Transcription Factor (MITF))
-
别名
- MITF
-
背景
- This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
-
分子量
-
Observed_MW: 65kDa
Calculated_MW: 40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa
-
基因ID
- 4286
-
UniProt
- O75030
-
途径
- Chromatin Binding
抗原
-