SHANK2 抗体 (AA 879-908)
Quick Overview for SHANK2 抗体 (AA 879-908) (ABIN656710)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 879-908
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- SHANK2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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: "A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders." in: Journal of neurodevelopmental disorders, Vol. 10, Issue 1, pp. 15, (2018) (PubMed).
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: "A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders." in: Journal of neurodevelopmental disorders, Vol. 10, Issue 1, pp. 15, (2018) (PubMed).
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- SHANK2
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背景
- This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].
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分子量
- 158822
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基因ID
- 22941
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NCBI登录号
- NP_036441
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UniProt
- Q9UPX8
抗原
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