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MRPS12 抗体

This anti-MRPS12 antibody is a 兔 多克隆 antibody detecting MRPS12 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6566989
发货至: 中国

Quick Overview for MRPS12 抗体 (ABIN6566989)

抗原

See all MRPS12 抗体
MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

适用

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人, 小鼠, 大鼠

宿主

  • 27
  • 1

克隆类型

  • 28
多克隆

标记

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This MRPS12 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human MRPS12

    亚型

    IgG
  • 应用备注

    WB 1:1000 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

    别名

    MRPS12

    背景

    Synonyms: 28S ribosomal protein S12,28S ribosomal protein S12 mitochondrial,mitochondrial,Mitochondrial ribosomal protein S12,MRP-S12,MRPS12,MT-RPS12,RPMS12,RPS12,RPSM12,RT12,S12mt

    Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.

    分子量

    Observed_MW: 14kDa

    Calculated_MW: 15kDa

    基因ID

    6183

    UniProt

    O15235

    途径

    Sensory Perception of Sound
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