Cadherin 4 抗体
Quick Overview for Cadherin 4 抗体 (ABIN6566983)
抗原
See all Cadherin 4 (CDH4) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human CDH4
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亚型
- IgG
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应用备注
- WB 1:1000 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cadherin 4 (CDH4)
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别名
- R-Cadherin
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背景
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Synonyms: CADH4,Cadherin 4,Cadherin-4,cdh4,R CAD,R-CAD,R-cadherin,Retinal cadherin
Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 100kDa
Calculated_MW: 92kDa/100kDa
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基因ID
- 1002
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UniProt
- P55283
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途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
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