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TPMT 抗体

The 兔 多克隆 anti-TPMT antibody (ABIN6566801) specifically detects TPMT in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6566801
发货至: 中国
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Room 801-803
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Quick Overview for TPMT 抗体 (ABIN6566801)

抗原

See all TPMT 抗体
TPMT (Thiopurine S-Methyltransferase (TPMT))

适用

  • 55
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宿主

  • 46
  • 9

克隆类型

  • 32
  • 23
多克隆

标记

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  • 2
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This TPMT antibody is un-conjugated

应用范围

  • 43
  • 26
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  • 6
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Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human TPMT (NP_000358.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TPMT (Thiopurine S-Methyltransferase (TPMT))

    别名

    TPMT

    背景

    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

    分子量

    Observed_MW: 28kDa

    Calculated_MW: 28kDa

    基因ID

    7172

    UniProt

    P51580
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