IKAP/p150 抗体
-
- 抗原 See all IKAP/p150 (ELP1) 抗体
- IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IKAP/p150 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human IKBKAP
- 亚型
- IgG
- Top Product
- Discover our top product ELP1 Primary Antibody
-
-
- 应用备注
- WB 1:1000 - 1:4000
- 限制
- 仅限研究用
-
- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))
- 别名
- IKBKAP (ELP1 产品)
- 背景
-
Synonyms: DKFZp781H1425,DYS,Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III),Elongator complex protein 1,ELP 1,ELP1,ELP1,FD,FLJ12497,IKAP,IkappaB kinase complex associated protein,IkappaB kinase complex-associated protein,ikbkap,IKI 3,IKI3,IKK complex associated protein,IKK complex-associated protein,Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein,OTTHUMP00000063889,p150,TOT 1,TOT1
Background: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
-
Observed_MW: 150kDa
Calculated_MW: 150kDa
- 基因ID
- 8518
- UniProt
- O95163
-