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Desmocollin 1 抗体

This anti-Desmocollin 1 antibody is a 兔 多克隆 antibody detecting Desmocollin 1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6566762
发货至: 中国

Quick Overview for Desmocollin 1 抗体 (ABIN6566762)

抗原

See all Desmocollin 1 (DSC1) 抗体
Desmocollin 1 (DSC1)

适用

人, 小鼠, 大鼠

宿主

  • 39
  • 4
  • 1

克隆类型

  • 38
  • 6
多克隆

标记

  • 30
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Desmocollin 1 antibody is un-conjugated

应用范围

  • 34
  • 20
  • 16
  • 10
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human DSC1

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Desmocollin 1 (DSC1)

    别名

    DSC1

    背景

    Synonyms: Cadherin family member 1,CDHF1,Desmocollin1,Desmosomal glycoprotein 2/3,DG2/DG3,DSC 1,DSC1

    Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.

    分子量

    Observed_MW: 105kDa

    Calculated_MW: 93kDa/99kDa

    基因ID

    1823

    UniProt

    Q08554
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