BCR 抗体
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北京 101111
Quick Overview for BCR 抗体 (ABIN6566471)
抗原
See all BCR 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human BCR
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亚型
- IgG
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anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibodyBCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibodyBCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (N-Term) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibodyBCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibodyBCR 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- BCR (Breakpoint Cluster Region (BCR))
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别名
- BCR
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背景
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Synonyms: ALL,bcr,BCR/ABL FUSION GENE,INCLUDED,BCR/FGFR1 chimera protein,BCR/FGFR1 FUSION GENE,INCLUDED,BCR/PDGFRA FUSION GENE,INCLUDED,BCR,BCR1,Breakpoint cluster region,Breakpoint cluster region protein,CML,D22S11,D22S662,FGFR1/BCR chimera protein,PHL,Renal carcinoma antigen NY-REN-26
Background: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 150kDa
Calculated_MW: 137kDa/142kDa
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基因ID
- 613
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UniProt
- P11274
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途径
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
抗原
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