IRF4 抗体 (AA 164-191)
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北京 101111
Quick Overview for IRF4 抗体 (AA 164-191) (ABIN656568)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 164-191
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 amino acids from the Central region of human IRF4.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- IRF4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- IRF4
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背景
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 51772
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基因ID
- 3662
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NCBI登录号
- NP_001182215, NP_002451
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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