CYP2S1 抗体 (C-Term)
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Quick Overview for CYP2S1 抗体 (C-Term) (ABIN656566)
抗原
See all CYP2S1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 399-428, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human CYP2S1.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).
: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." in: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).
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: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).
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- CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))
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别名
- CYP2S1
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背景
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.
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分子量
- 55817
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基因ID
- 29785
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NCBI登录号
- NP_085125
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UniProt
- Q96SQ9
抗原
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