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SESN3 抗体 (AA 320-347)

Cited in 2+ publications. The 兔 多克隆 anti-SESN3 antibody (Clone RB18605) (ABIN656403) specifically detects SESN3 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN656403
发货至: 中国
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Quick Overview for SESN3 抗体 (AA 320-347) (ABIN656403)

抗原

See all SESN3 抗体
SESN3 (Sestrin 3 (SESN3))

适用

  • 42
  • 18
  • 18

宿主

  • 39
  • 3

克隆类型

  • 41
  • 1
多克隆

标记

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This SESN3 antibody is un-conjugated

应用范围

  • 35
  • 15
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB18605
  • 抗原表位

    • 15
    • 6
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    • 2
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    • 2
    • 1
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    AA 320-347

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Sestrin-3 Antibody (Center Y335) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Kimball, Ravi, Gordon, Dennis, Jefferson: "Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet." in: The Journal of nutrition, Vol. 145, Issue 11, pp. 2496-502, (2015) (PubMed).

    Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

  • 抗原

    SESN3 (Sestrin 3 (SESN3))

    别名

    Sestrin-3

    背景

    Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.

    分子量

    57291

    基因ID

    143686

    NCBI登录号

    NP_653266

    UniProt

    P58005
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